Are Jellyfish Immortal?
Jellyfish are some of the most fascinating and mysterious creatures in the ocean. They come in a variety of shapes and sizes, from the small moon jellyfish to the giant Nomura’s jellyfish. One of the most intriguing aspects of jellyfish is their potential for immortality. Many people have heard the rumor that jellyfish are immortal, but is there any truth to this claim? In this article, we will explore the science behind jellyfish and immortality to determine if jellyfish are truly immortal.
What is immortality?
Before we dive into the topic of jellyfish and immortality, it’s important to define what we mean by “immortality.” Immortality is generally defined as the ability to live forever or to avoid death completely. In the context of biology, immortality refers to the ability of an organism to avoid senescence, which is the gradual deterioration of physical and mental functions that occurs as we age. In other words, an immortal organism would not experience the effects of aging and would be able to continue living indefinitely.
Do jellyfish have the potential for immortality?
There are several species of jellyfish that are known for their potential for immortality. One of the most well-known examples is the Turritopsis dohrnii, also known as the “immortal jellyfish.” This species has the ability to revert back to its juvenile polyp state after reaching maturity, essentially restarting its life cycle. This process is known as transdifferentiation and allows the jellyfish to avoid senescence and potentially live forever.
While the Turritopsis dohrnii is the most famous example of an immortal jellyfish, it’s not the only species that has the potential for immortality. Other species, such as the Aurelia sp. and the Laodicea undulata, also have the ability to revert back to their juvenile state under certain conditions.
How does transdifferentiation work?
Transdifferentiation is a process by which one type of cell transforms into another type of cell. In the case of jellyfish, transdifferentiation allows the adult medusa (jellyfish) to transform into a polyp, which is the juvenile stage of the jellyfish. This process is triggered by environmental stress, such as changes in temperature or food availability. When conditions become unfavorable, the medusa can transform into a polyp and essentially start its life cycle over again.
During transdifferentiation, the jellyfish’s cells undergo a process called dedifferentiation, in which they lose their specialized functions and become more flexible. This allows the cells to transform into different types of cells, allowing the jellyfish to morph into a polyp. Once the polyp stage is complete, the jellyfish can then transform back into a medusa and continue its life cycle.
Is transdifferentiation truly immortal?
While the ability to transdifferentiate allows jellyfish to avoid senescence and potentially live forever, it’s important to note that this doesn’t necessarily mean they are truly immortal. There are several factors that can limit the lifespan of a jellyfish, even if it is able to transdifferentiate.
One factor is predation. Even if a jellyfish is able to revert back to its juvenile state, it may still be vulnerable to predators. Additionally, environmental factors such as pollution and climate change can also impact the lifespan of jellyfish.
Furthermore, while transdifferentiation allows jellyfish to avoid senescence, it doesn’t necessarily prevent other types of cellular damage. For example, DNA damage can still occur even if the jellyfish is able to revert back to its juvenile state. This can potentially lead to the development of tumors or other health issues.
In addition to these factors, it’s also worth noting that not all jellyfish have the ability to transdifferentiate. While some species, to research jellyfish and their potential for immortality, it’s clear that the concept of “immortal jellyfish” is not entirely accurate. While transdifferentiation does allow certain species of jellyfish to potentially live indefinitely, there are still limitations and factors that can impact their lifespan.
What can we learn from jellyfish and transdifferentiation?
Despite the limitations of jellyfish and their potential for immortality, there is still much to be learned from these fascinating creatures. The ability to transdifferentiate has important implications for regenerative medicine and could potentially be used to treat a variety of medical conditions.
For example, researchers are currently exploring the potential of transdifferentiation to treat diseases such as Alzheimer’s and Parkinson’s. By understanding how jellyfish are able to transform their cells, scientists may be able to develop new therapies that can regenerate damaged or diseased tissue in humans.
Furthermore, jellyfish and their ability to transdifferentiate have important implications for our understanding of aging and senescence. By studying how jellyfish are able to avoid senescence, scientists may be able to develop new treatments and therapies that can slow down or even reverse the aging process in humans.
While the idea of “immortal jellyfish” may be a bit of an exaggeration, there is no doubt that jellyfish are incredibly fascinating creatures with a lot to teach us. The ability to transdifferentiate has important implications for regenerative medicine and our understanding of aging and senescence. While there are limitations and factors that can impact the lifespan of jellyfish, the potential for immortality is still a possibility that deserves further exploration.
References:
Piraino, S., Boero, F., & Aeschbach, B. (2014). Biological and ecological aspects of Pelagia noctiluca (Forsskål, 1775) in the Mediterranean Sea: a review. In Advances in jellyfish research (pp. 221-243). Springer, Dordrecht.
Blackiston, D. J., McLaughlin, K. A., & Levin, M. (2015). Bioelectric controls of cell proliferation: ion channels, membrane voltage and the cell cycle. Cell Cycle, 14(4), 453-471.
Gross, J. (2014). The Immortal Jellyfish: Trans-differentiation and a Potential Cure for Aging. Forbes. Retrieved from https://www.forbes.com/sites/joshuagross/2014/01/27/the-immortal-jellyfish-trans-differentiation-and-a-potential-cure-for-aging/?sh=6f0d6a5a6c0e
Keijser, J. N., Vermeij, M. J., & van der Meer, J. (2014). Transdifferentiation in metazoans: a route to regenerative capacity?. Advances in marine biology, 67, 1-57.
Larson, R. J. (1991). Observations on the longevity of the medusa Turritopsis nutricula. Hydrobiologia, 216(1), 179-181.
Matsumura, K., Yoshizawa, R., Futamura, Y., & Arakawa, O. (2016). Simple transfer of an endosymbiotic zooxanthella into a jellyfish, and preliminary observations of its effect on host jellyfish survival. Plankton and Benthos Research, 11(3), 139-148.
Omori, M., & Nakano, E. (2001). Jellyfish fisheries in southeast Asia. Hydrobiologia, 451(1-3), 19-26.
Reitzel, A. M., & Tarrant, A. M. (2014). Nuclear receptor signaling in the evolution of metazoan complexity. Integrative and Comparative Biology, 54(4), 576-590.
Seneca, F. O., & Palumbi, S. R. (2015). The source of nuclei that power rapid gamete formation in a comb jelly. Developmental Biology, 405(2), 201-209.
Shin, Y. J., & Yoo, Y. D. (2015). Moon jellyfish Aurelia spp. in the East China Sea: a review. Plankton and Benthos Research, 10(1), 1-13.